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TRANSDERMAL MEDICATIONS

What is transdermal therapy?
The skin is the body’s largest organ, and as such, provides an excellent route for administration and absorption of numerous medications. Novel bases allow compounding pharmacists to prepare transdermal formulations that are applied topically, but can be absorbed into subcutaneous tissues or the systemic circulation. With the utilization of transdermal bases, local concentrations of the active medications can be achieved that are higher than those obtained using oral or injectable routes. Read more below!

 












What are the benefits to transdermal therapy?

  • Ease of application
  • Local concentrations of the active medications can be achieved that are higher than those obtained using oral or injectable routes
  • Transdermal therapy reduces drug side-effects because the patient’s kidneys and/or liver exposure to the active ingredients is eliminated or greatly reduced. Further, gastrointestinal difficulties, that are often seen with the oral administration of pain relieving and anti-inflammatory drugs, are eliminated.

Conditions that transdermal therapy may benefit:

A number of medical conditions, often associated with chronic pain, that may be treated by utilizing a transdermal delivery of active medications include, among others:

  • Bursitis
  • Cranio-facial neuralgia
  • Diabetic neuropathy
  • Epicondylitis
  • Gout
  • Nausea and vomiting
  • Neuropathic pain
  • Psoriasis
  • Reflex Sympathetic Dystrophy Syndrome (RSDS, RSD)
  • Sport injuries
  • Tendonitis
  • TMJ
  • Trauma to wrists, ankles, fingers and toes
  • Vascular diseases
  • Patients unable or unwilling to use oral, injectable, or rectal medications
  • An uncooperative pet

Where are transdermal medications applied?

  • To trigger points, or the site of back or joint pain or TMJ disorder – e.g., analgesic or anti-inflammatory
  • To the arm, wrist, or behind the ear for systemic effect - e.g., antiemetic or hormone replacement therapy
  • To the inside of an animal’s ear or another closely clipped or hairless area – e.g., antiemetic, cardiac, or behavioral therapy

For more information

Article: Trans-Dermal Treatment of Pain