|
Anti-fungal Therapy: Fungal infections of the
feet are commonly associated with dry, cracked skin surrounding
the plantar surface and heel fissures. Research points
to the practicality of using ibuprofen, alone or in combination
with azole antifungals. Higher cure rates can be achieved
with combing therapy with high concentrations of urea cream,
especially when treating areas with significant calluses.
Nail Removal: Urea plasters have been shown to
be effective for non-surgical removal of traumatized, dystrophic,
or diseased nails. The use of urea plasters can be much
less costly, several nails can be treated in one session, and
the procedure is essentially painless. Because there
is a significant decreased risk of infection or hemorrhage,
the procedure is ideal for treating diabetics and others with
vascular insufficiency and peripheral neuropathy.
Warts: Customized medications can be compounded
for the treatment of warts [i.e. cimetidine, glutaraldehyde,
cantharidin, or squaric acid dibutylester (SADBE)], plantar
warts (sodium salicylate), and molluscum contagiosum (potassium
hydroxide).
Topical Therapy for Oral and Peri-Oral Pain and Infections: We
have developed vehicle-carrier agents and bases that can penetrate
the mucosa and cutaneous tissues and transport active ingredients
to the treatment site. Several topical intraoral medications
are used in the treatment of oral ulcerations and infections,
including antifungals; nonsteroidal anti-inflammatory drugs
(NSAIDs); and corticosteroids. Medicated lollipops, lozenges,
and adhering powders can increase contact time with the mucosa.
Treatments for Dry mouth, Stomatitis, and Mucositis
Suppressing the Gag Reflex: An electrolyte tablet
administered and retained intraorally a few minutes before
the start of a procedure can suppress the gag reflex, allowing
a mandibular block to be given with much greater ease, which
further reduces the gagging reflex. Tablets can be
prescribed for home use for patients who can not properly
perform oral hygiene procedures due to the gagging problem. Some
patients and dentists prefer to use electrolyte lollipops.
Transdermal Anti-Emetics: Topical application
of anti-emetics in a gel formulation provides a rapid onset
and offers an effective alternative to oral administration.
Therapy for Temporo-Mandibular Joint Disorder (TMJ): Transdermal
application of NSAIDs such as ketoprofen results in significant
tissue levels beneath the site of application. Additionally,
side effects such as gastrointestinal irritation are avoided.
Peridontal Therapy: Compounding allows countless
active ingredients to be incorporated into customized mouthwashes,
gels, troches, etc. For example, to treat periodontal
disease, antibiotics can be formulated as a mouthwash, or added
to an oral adhesive paste or a plasticized gel that will maintain
the contact between the tissue and medication for a longer
period of time.
“Miracle Mouthwashes”: Compounding
dental mouthwashes or rinses may offer numerous advantages
over commercially available dosage forms. A customized
preparation prepared using pharmaceutical grade bulk powders
can eliminate concerns of palatability, limit alcohol content,
and eliminate dyes which may stain exposed mucosa. Various
preparations are also available to treat burning mouth syndrome
and anesthetic/analgesic and antibiotic/anti-infective mouthwashes
are commonly requested.
Hyperhidrosis: Various topical compounded medications
can be prepared to relieve excessive perspiration.
Hemorrhoids: Treatment often involve use of a novel
dosage form known as the “rectal rocket”, a suppository
that permits simultaneous internal and external application of
corticosteroids, topical anesthetics, antibiotics, or other medications. |
